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image 1 of 8
star, score, rank, reviewHighly Rated
Nike Run Defy Women's Road Running Shoes - Black/Hyper Pink/Pink Foam/Elemental Pink

Nike Run Defy

Women's Road Running Shoes

$65

Extra 20% off w/ code SUMMER

star, score, rank, reviewHighly Rated
  • Nike Run Defy Women's Road Running Shoes - Black/Hyper Pink/Pink Foam/Elemental Pink
Black/Hyper Pink/Pink Foam/Elemental Pink
Black/Wolf Grey/White
White/Black/Pure Platinum
White/Football Grey/Work Blue/Blue Void
Summit White/White/Malachite/Metallic Silver
Sail/Summit White/Chalk/White
Particle Rose/Sail/Tattoo/Hydrogen Blue
Select Sizeruler, dimension, size, lengthSize Guide

Shipping

You'll see our shipping options at checkout.
Free Pickup
  • Shown: Black/Hyper Pink/Pink Foam/Elemental Pink
  • Style: HM9593-001

Nike Run Defy

$65

Run by your own rules in the all-new Nike Run Defy. A foam midsole, breathable upper and reliable traction combine to make a shoe that’s raring for runs of all lengths and paces.

Key Features

  • Mesh on upper adds breathability.
  • Foam midsole delivers a soft ride.
  • Flex grooves create a cushioned effect for your run.
  • Waffle outsole is made of a durable, flexible material that helps keep you on the move.
  • Increased rubber at the outsole provides traction and durability.

Product Details

  • Weight: Approx. 233 g/8.2 oz (Women’s US 8)
  • Heel-to-toe drop: 10 mm
  • Shown: Black/Hyper Pink/Pink Foam/Elemental Pink
  • Style: HM9593-001

Shipping & Returns

Free standard shipping on orders $50+ and free 60-day returns for Nike Members. Learn more. Return policy exclusions apply.

Pick-up available at select Nike Stores.

Reviews (222)

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star, score, rank, reviewstar, score, rank, reviewstar, score, rank, reviewstar, score, rank, reviewstar, score, rank, reviewstar, score, rank, review

4.7 Stars

  • Light and comfy

    star, score, rank, reviewstar, score, rank, reviewstar, score, rank, reviewstar, score, rank, reviewstar, score, rank, review

    yvonne316218676 - Jun 16, 2026

    Very lightweight and comfortable. Fit perfect. A little narrow in the front but most Nikes are narrow. If you have wide feet than I’d suggest you size up. I did not have to size up. Very happy with them.

  • Great value

    star, score, rank, reviewstar, score, rank, reviewstar, score, rank, reviewstar, score, rank, reviewstar, score, rank, review

    Renee - Jun 07, 2026

    I loved these Nikes so much, I bought myself 3 pairs and one for my daughter. Great value and set one pair aside as my “inside shoes” that are only worn in the house. Very comfortable and durable.

  • Dream Comfort Sneakers

    star, score, rank, reviewstar, score, rank, reviewstar, score, rank, reviewstar, score, rank, reviewstar, score, rank, review

    Donna - Jun 06, 2026

    These sneakers are a excellent in comfort, fit, stability, price. I’d like to buy a couple more pairs in different colors!

See Reviews
Nike Run Defy Women's Road Running Shoes

Nike Run Defy

$65

Breathable upper, reliable traction and foam midsole deliver all day comfort.

Engineered For

Road Running

Cushion

All Day Comfort

Shoe Weight

Approx. 233g/8.2oz (Women’s US 8)

Heel-to-Toe Drop

10mm

Tech Specs

Shoe Weight

Approx. 233g/8.2oz (Women’s US 8)

Heel-to-Toe Drop

10mm

Features That Perform

  • Mesh Upper

    Mesh on the upper adds breathability.

  • Foam Midsole

    Foam midsole delivers a soft ride.

  • Waffle Outsole

    Waffle outsole is a made of a durable, flexible material that helps keep you on the move.

Complete the Look

  • Nike One Women's High-Waisted 7/8 Leggings with Pockets
    Nike Run Defy Women's Road Running Shoes
    Nike Everyday Elevated Ankle Socks (3 Pairs)
    Nike One Relaxed Women's Dri-FIT Long-Sleeve Top
    Nike Swoosh Light Support Women's Non-Padded Sports Bra
  • Nike Attack Women's Dri-FIT Fitness Mid-Rise 5" Unlined Shorts
    Nike Recharge Stainless Steel Chug Bottle (32 oz)
    Nike Dri-FIT Women's Training Tank
    Nike Alate Minimalist Women's Light-Support Padded Convertible Sports Bra
    Nike Run Defy Women's Road Running Shoes
  • Nike Run Defy Women's Road Running Shoes
    Nike Sportswear Phoenix Fleece Women's Oversized Logo Hoodie
    Nike One Seamless Front Women's High-Waisted Full-Length Leggings
    Nike Sportswear Club Essentials Women's T-Shirt
    Nike Indy Women's Light-Support Sports Bra
Item 3 of 3

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