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Highly Rated
Nike Run Defy Women's Road Running Shoes - Particle Rose/Sail/Tattoo/Hydrogen Blue

Nike Run Defy

Women's Road Running Shoes

$65
Black/Wolf Grey/White
White/Black/Pure Platinum
Sweet Beet/Black/White/Sweet Beet
Ghost/Summit White/Football Grey/Midnight Navy
Particle Rose/Sail/Tattoo/Hydrogen Blue
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Free Pickup
  • Shown: Particle Rose/Sail/Tattoo/Hydrogen Blue
  • Style: HM9593-606

Nike Run Defy

$65

Run by your own rules in the all-new Nike Defy. A foam midsole, breathable upper and reliable traction combine to make a shoe that’s raring for runs of all lengths and paces.

Key Features

  • Mesh on upper adds breathability.
  • Foam midsole delivers a soft ride.
  • Flex grooves create a cushioned effect for your run.
  • Waffle outsole is a made of a durable, flexible material that helps keep you on the move.
  • Increased rubber at the outsole provides traction and durability.

Product Details

  • Weight: Approx. 233 g/8.2 oz (Women’s US 8)
  • Heel-to-toe drop: 10 mm
  • Shown: Particle Rose/Sail/Tattoo/Hydrogen Blue
  • Style: HM9593-606

Shipping & Returns


Pick-up available at select Nike Stores.

Reviews (104)

4.8 Stars

  • Beautiful hot weather shoe

    Purplelover - Dec 06, 2025

    Colorful Shoe

  • Super comfortable

    denitsad785901351 - Nov 30, 2025

    Very comfortable and light, nice design

  • Recommend

    Linda - Nov 30, 2025

    [This review was collected as part of a promotion.] So comfy! Not to bulky also a great everyday shoe!

    Product received for free, or reviewed as part of a sweepstakes/giveaway or in exchange for a discount.
    #teamnike

Breathable upper, reliable traction and foam midsole deliver all day comfort.

Engineered For

Road Running

Cushion

All Day Comfort

Shoe Weight

Approx. 233g/8.2oz (Women’s US 8)

Heel-to-Toe Drop

10mm

Tech Specs

Shoe Weight

Approx. 233g/8.2oz (Women’s US 8)

Heel-to-Toe Drop

10mm

Complete the Look