Nike Run Defy

Women's Road Running Shoes

$65

Extra 20% off w/ code SUMMER

Highly Rated

Black/Hyper Pink/Pink Foam/Elemental Pink

Summit White/White/Malachite/Metallic Silver

You'll see our shipping options at checkout.

Free Pickup

Shown: Summit White/White/Malachite/Metallic Silver
Style: HM9593-122

Nike Run Defy

$65

Run by your own rules in the all-new Nike Run Defy. A foam midsole, breathable upper and reliable traction combine to make a shoe that’s raring for runs of all lengths and paces.

Key Features

Mesh on upper adds breathability.
Foam midsole delivers a soft ride.
Flex grooves create a cushioned effect for your run.
Waffle outsole is made of a durable, flexible material that helps keep you on the move.
Increased rubber at the outsole provides traction and durability.

Product Details

Weight: Approx. 233 g/8.2 oz (Women’s US 8)
Heel-to-toe drop: 10 mm
Shown: Summit White/White/Malachite/Metallic Silver
Style: HM9593-122

Shipping & Returns

Pick-up available at select Nike Stores.

Reviews (215)

4.7 Stars

Light and comfy
yvonne316218676Jun 16, 2026
Very lightweight and comfortable. Fit perfect. A little narrow in the front but most Nikes are narrow. If you have wide feet than I’d suggest you size up. I did not have to size up. Very happy with them.
So comfy
Stephanie585313318Jun 03, 2026
I work a 19 hour day on my feet almost the whole time . These shoes are comfortable the whole day ,supportive and look great. They are also great quality most shoes last me a couple months ,im super hard on shoes .these shoes have already lasted me 9 months and still have life in them. I dont use these shoes for running
Comfortable shoes, Great for walking!
dellad829812244Jun 01, 2026
I absolutely love these Nikes. They are so comfortable. I walk a lot at work and they are awesome.