
Nike Run Defy
Women's Road Running Shoes
Extra 25% Off w/ code: DAYONE
Shipping
You'll see our shipping options at checkout.- Shown: Summit White/White/Malachite/Metallic Silver
- Style: HM9593-122
Nike Run Defy
Run by your own rules in the all-new Nike Run Defy. A foam midsole, breathable upper and reliable traction combine to make a shoe that’s raring for runs of all lengths and paces.
Key Features
- Mesh on upper adds breathability.
- Foam midsole delivers a soft ride.
- Flex grooves create a cushioned effect for your run.
- Waffle outsole is made of a durable, flexible material that helps keep you on the move.
- Increased rubber at the outsole provides traction and durability.
Product Details
- Weight: Approx. 233 g/8.2 oz (Women’s US 8)
- Heel-to-toe drop: 10 mm
- Shown: Summit White/White/Malachite/Metallic Silver
- Style: HM9593-122
Shipping & Returns
Reviews (244)
Reviews (244)
What Reviewers Say
These shoes earn widespread praise for exceptional comfort and support, making them ideal for extended wear—whether working long shifts, walking, or light running. The lightweight, breathable design and generous cushioning deliver all-day comfort without fatigue. Fit tends to run snug and narrow, so sizing up a half size is recommended, especially for wider feet. The sleek, versatile style pairs easily with various outfits, and the shoes require little to no break-in period.
AI-generated summary

Nike Run Defy
Breathable upper, reliable traction and foam midsole deliver all day comfort.
Engineered For
Road Running
Cushion
All Day Comfort
Shoe Weight
Approx. 233g/8.2oz (Women’s US 8)
Heel-to-Toe Drop
10mm
Tech Specs
Shoe Weight
Approx. 233g/8.2oz (Women’s US 8)
Heel-to-Toe Drop
10mm













