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Highly Rated
Nike Run Defy Women's Road Running Shoes - White/Smoke Grey/Black

Nike Run Defy

Women's Road Running Shoes

$65
Black/Hyper Pink/Pink Foam/Elemental Pink
Black/Wolf Grey/White
Black/Anthracite
Light Orewood Brown/Cave Stone/White/College Grey
White/Black/Pure Platinum
White/Smoke Grey/Black
White/Football Grey/Work Blue/Blue Void
Summit White/White/Malachite/Metallic Silver
Sail/Summit White/Chalk/White
Particle Rose/Sail/Tattoo/Hydrogen Blue
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  • Shown: White/Smoke Grey/Black
  • Style: HM9593-101

Nike Run Defy

$65

Run by your own rules in the all-new Nike Run Defy. A foam midsole, breathable upper and reliable traction combine to make a shoe that’s raring for runs of all lengths and paces.

Key Features

  • Mesh on upper adds breathability.
  • Foam midsole delivers a soft ride.
  • Flex grooves create a cushioned effect for your run.
  • Waffle outsole is made of a durable, flexible material that helps keep you on the move.
  • Increased rubber at the outsole provides traction and durability.

Product Details

  • Weight: Approx. 233 g/8.2 oz (Women’s US 8)
  • Heel-to-toe drop: 10 mm
  • Shown: White/Smoke Grey/Black
  • Style: HM9593-101

Shipping & Returns


Pick-up available at select Nike Stores.

Reviews (231)

What Reviewers Say

Praised for exceptional comfort and lightweight construction, these shoes deliver cushioning and support that holds up through long shifts, workouts, and extended walking. Fit tends to run snug and narrow—sizing up a half size is recommended, especially for wider feet. The breathable design and versatile style make them ideal for gym sessions, everyday wear, and all-day comfort.

AI-generated summary

Breathable upper, reliable traction and foam midsole deliver all day comfort.

Engineered For

Road Running

Cushion

All Day Comfort

Shoe Weight

Approx. 233g/8.2oz (Women’s US 8)

Heel-to-Toe Drop

10mm

Tech Specs

Shoe Weight

Approx. 233g/8.2oz (Women’s US 8)

Heel-to-Toe Drop

10mm

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