image 1 of 8
Highly Rated
Nike Run Defy Women's Road Running Shoes - Ghost/Summit White/Football Grey/Midnight Navy

Nike Run Defy

Women's Road Running Shoes

$52.9718%

Extra 25% off w/ code BFRIDAY

Black/Hyper Pink/Pink Foam/Elemental Pink
Black/Wolf Grey/White
White/Black/Pure Platinum
Mint Foam/Cannon/Bleached Turquoise/White
Particle Pink/Soft Pearl/Washed Coral/Orange Chalk
Sweet Beet/Black/White/Sweet Beet
Ghost/Summit White/Football Grey/Midnight Navy
Select SizeSize Guide

Shipping

You'll see our shipping options at checkout.
Free Pickup
  • Shown: Ghost/Summit White/Football Grey/Midnight Navy
  • Style: HM9593-005

Nike Run Defy

$52.9718%

Run by your own rules in the all-new Nike Defy. A foam midsole, breathable upper and reliable traction combine to make a shoe that’s raring for runs of all lengths and paces.

Key Features

  • Mesh on upper adds breathability.
  • Foam midsole delivers a soft ride.
  • Flex grooves create a cushioned effect for your run.
  • Waffle outsole is a made of a durable, flexible material that helps keep you on the move.
  • Increased rubber at the outsole provides traction and durability.

Product Details

  • Weight: Approx. 233 g/8.2 oz (Women’s US 8)
  • Heel-to-toe drop: 10 mm
  • Shown: Ghost/Summit White/Football Grey/Midnight Navy
  • Style: HM9593-005

Shipping & Returns


Pick-up available at select Nike Stores.

Reviews (94)

4.8 Stars

  • KarenA33293193 - Nov 16, 2025

    Looking for a sneaker not too over priced and would last a few years, mainly for walking and gym. Silver swoop on the black means it will match a lot of wardrobe items.

  • running shoes

    long time macy shopper - Nov 09, 2025

    shoes comfortable. can wear for long periods of time

  • Disappointing.

    Rosey54e0297a35514fdbb4d7de26b47ff003 - Nov 09, 2025

    The first, most obvious issue was that the laces are too short - There's barely enough to tie them into a bow. Then it was clear pretty quickly that there's not enough arch support. I tried adding small arch inserts on top of the original insert, but there's not enough depth in the shoe to allow for that - the arch and my foot cannot both fit inside. Then I tried removing the original inserts and putting in more supportive ones. Again, with the thicker inserts, my foot feels like it's being pushed up out of the shoe. The shoes also gape open near the top lace holes every time I take a step. Overall, these are the worst Nikes I've owned. I understand why they were cheap. I've been mostly continuing to wear my old sneakers because these just aren't it.

Breathable upper, reliable traction and foam midsole deliver all day comfort.

Engineered For

Road Running

Cushion

All Day Comfort

Shoe Weight

Approx. 233g/8.2oz (Women’s US 8)

Heel-to-Toe Drop

10mm

Tech Specs

Shoe Weight

Approx. 233g/8.2oz (Women’s US 8)

Heel-to-Toe Drop

10mm

Complete the Look