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Highly Rated
Nike Run Defy Women's Road Running Shoes - White/Football Grey/Work Blue/Blue Void

Nike Run Defy

Women's Road Running Shoes

26% off
Black/Hyper Pink/Pink Foam/Elemental Pink
Black/Wolf Grey/White
Black/Anthracite
White/Black/Pure Platinum
Elemental Pink/Silt Red/Black/White
White/Smoke Grey/Black
White/Football Grey/Work Blue/Blue Void
Dark Smoke Grey/Aluminum/Football Grey/White
Select SizeSize Guide
  • Fits small; we recommend ordering a half size up

Shipping

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Free Pickup
  • Shown: White/Football Grey/Work Blue/Blue Void
  • Style: HM9593-109

Nike Run Defy

26% off

Run by your own rules in the all-new Nike Run Defy. A foam midsole, breathable upper and reliable traction combine to make a shoe that’s raring for runs of all lengths and paces.

Key Features

  • Mesh on upper adds breathability.
  • Foam midsole delivers a soft ride.
  • Flex grooves create a cushioned effect for your run.
  • Waffle outsole is made of a durable, flexible material that helps keep you on the move.
  • Increased rubber at the outsole provides traction and durability.

Product Details

  • Weight: Approx. 233 g/8.2 oz (Women’s US 8)
  • Heel-to-toe drop: 10 mm
  • Shown: White/Football Grey/Work Blue/Blue Void
  • Style: HM9593-109

Size & Fit

    • Fits small; we recommend ordering a half size up
  • Size Guide

Shipping & Returns


Pick-up available at select Nike Stores.

Reviews (322)

What Reviewers Say

These shoes deliver exceptional comfort with generous cushioning that supports all-day wear, from gym sessions to long shifts on your feet. Lightweight and breathable, they work well for running, walking, and everyday activities. Sizing tends to run small and narrow—going up a half size is recommended, especially for wider feet. The clean design pairs easily with various outfits, and the fit stays true once sized correctly.

AI-generated summary

Breathable upper, reliable traction and foam midsole deliver all day comfort.

Engineered For

Road Running

Cushion

All Day Comfort

Shoe Weight

Approx. 233g/8.2oz (Women’s US 8)

Heel-to-Toe Drop

10mm

Tech Specs

Shoe Weight

Approx. 233g/8.2oz (Women’s US 8)

Heel-to-Toe Drop

10mm

Complete the Look