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Highly Rated
Nike Run Defy Men's Road Running Shoes - Black/White

Nike Run Defy

Men's Road Running Shoes

$65
Black/White
White/Black
Summit White/Turf Orange/White/Bright Crimson
Black/Dark Hazel/Light Khaki/Black
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Run by your own rules in the Nike Run Defy. A foam midsole, breathable upper and reliable traction combine to make a shoe that’s ready for runs of all lengths and paces.


  • Shown: Black/White
  • Style: HM9594-004

Nike Run Defy

$65

Waffle outsole and flex grooves help keep you cushioned and stable.

Run by your own rules in the Nike Run Defy. A foam midsole, breathable upper and reliable traction combine to make a shoe that’s ready for runs of all lengths and paces.

Mesh on Upper

Mesh on upper adds breathability.

Foam Midsole

Foam midsole delivers a soft ride.

Flex Grooves

Flex grooves create a cushioned effect for your run.

Waffle Outsole

Waffle outsole is a made of a durable, flexible material that helps keep you on the move.

Product Details

  • Weight: Approx. 281g/9.9oz (Men's US 10)
  • Heel-to-toe drop: 10mm
  • Shown: Black/White
  • Style: HM9594-004

Shipping & Returns


Pick-up available at select Nike Stores.

Reviews (189)

What Reviewers Say

These shoes earn widespread praise for exceptional comfort and lightweight construction, with cushioning that feels plush underfoot. Fit tends to run narrow and small—sizing up a half size is recommended, especially for wider feet. The versatile design works well for running, walking, gym workouts, and all-day wear, pairing easily with casual outfits. Feedback highlights their supportive feel for extended standing and active use, though the toe box can feel snug.

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