Highly Rated
Nike Run Defy Men's Road Running Shoes - Black/Green Shock/White/Green Strike

Nike Run Defy

Men's Road Running Shoes

23% off
Black/Anthracite
Wolf Grey/White/Iron Grey/Black
Black/White
White/Black/Pure Platinum
Black/Green Shock/White/Green Strike
Wolf Grey/Black/White/Bright Crimson
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Run by your own rules in the Nike Run Defy. A foam midsole, breathable upper and reliable traction combine to make a shoe that’s ready for runs of all lengths and paces.


  • Shown: Black/Green Shock/White/Green Strike
  • Style: HM9594-006

Nike Run Defy

23% off

Waffle outsole and flex grooves help keep you cushioned and stable.

Run by your own rules in the Nike Run Defy. A foam midsole, breathable upper and reliable traction combine to make a shoe that’s ready for runs of all lengths and paces.

Mesh on Upper

Mesh on upper adds breathability.

Foam Midsole

Foam midsole delivers a soft ride.

Flex Grooves

Flex grooves create a cushioned effect for your run.

Waffle Outsole

Waffle outsole is a made of a durable, flexible material that helps keep you on the move.

Product Details

  • Weight: Approx. 281g/9.9oz (Men's US 10)
  • Heel-to-toe drop: 10mm
  • Shown: Black/Green Shock/White/Green Strike
  • Style: HM9594-006

Shipping & Returns


Pick-up available at select Nike Stores.

Reviews (66)

4.8 Stars

  • Good shoe

    Thomas496603693 - Nov 07, 2025

    Quality shoe at a fair price. A little tight on the sides, but fitting better with every wear.

  • Satisfied customer

    Kristy453058960 - Nov 07, 2025

    Even though I'm a woman, the size scaled down was perfect 👌. Great price, quality and fast delivery! Since I'm on my feet 9 hrs/day, these were a super purchase👍

  • Great Shoes

    777 - Oct 29, 2025

    Great shies

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